While navigating the Lateran, Ezio caused an old painting to fall, creating a shortcut.
- 埃齐奥: 现在我有办法回到这上面来了。
While jumping across several chandeliers, Ezio caused one of them to lower slightly, creating another shortcut.
- 埃齐奥 如果我掉下去了，那玩意儿可以帮我。
While jumping on to a platform of old floor, Ezio caused a plank to fall down, creating another shortcut.
- 埃齐奥: 如果我掉下去了，那可能会有所帮助。
After reaching a large church room, Ezio realized that the shrine was blocked by a large gate.
- 埃齐奥: Magnifico.（真壮观啊。）
While navigating the room, Ezio caused a fragile pillar to collapse, creating a shortcut.
- 埃齐奥: 太好了！如果我掉下去可以走那条路上来。
Ezio caused a chandelier to ram into a large cross. The cross fell over and destroyed the gate, gaining Ezio access to the shrine.
- 埃齐奥: 阿门。
Ezio retrieved a key and a Scroll of Romulus.
- This was the only Lair of Romulus that did not feature any Followers of Romulus.
- There were three Borgia flags available to find in the area.
- A Shrunken Head, one of the rarest trade objects required for the shop quest Exotica can be found in the room right from the shrine's door.