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Whitechapel is one of London's seven boroughs. During the Industrial Revolution, the region became a place of destitution, with its inhabitants often turning to begging, thievery, murder, and prostitution.
Controlled by the Templars through their gang, the Blighters lead by Rexford Kaylock, it was eventually conquered by the Assassin-lead gang, the Rooks, under Jacob and Evie Frye. In order to take over Whitechapel, Jacob and Evie Frye had to take down several threats. When they were dealt with, a Gang War would be arranged to take down the Templars' grip on the borough for good.
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Later, in 1888, the borough was the site of a series of gruesome murders, all of them being of prostitutes, which were attributed to a mysterious serial killer dubbed Jack the Ripper.