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On day 24 of year 2161 of the Isu Era, alongside his two counterparts, the "Father of Understanding" Yaldabaoth and the "Mother of Wisdom" Saklas, Samael was tasked to start the preparatory work for Project Anthropos, an Isu initiative to create a new workforce, the human species. While Yaldabaoth was in charge of the production and Saklas was responsible for the design, Samael recruited the talents required to achieve the project.
- Assassin's Creed: Valhalla (mentioned only)