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When Diktys found Danae and Perseus, the daughter and grandson of the Argive King Akrisios, and took them under his wing, Polydektes noticed Danae, and wanted her. Perseus opposed their union, however, and thus Polydektes decreed that Perseus should slay the gorgon Medusa, and bring back her head.
Perseus did as told, and when he returned with Medusa's head, showed it to Polydektes, who was turned to stone.
- Assassin's Creed: Odyssey (mentioned only)