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After 4 years of searching for Micheletto and Cesare, Ezio finally finds Cesare at the Siege of Viana. Ezio chases the Captain-General across the Spanish plains, trying not to get involved in the fighting. Ezio climbs a destroyed Borgia siege tower, and battles Cesare on Viana's battlements.
- Cesare Borgia is killed.
- The military might of the Borgia is lost.
- Ezio wonders where to hide the Apple of Eden.
- Cesare: How did you find me?!
- Ezio: The Apple you stole from Mario Auditore lead me here!