Nefertiti and her husband were known for a religious revolution, in which they worshiped one god only, Aten, or the sun disc. With her husband, she reigned at what was arguably the wealthiest period of Ancient Egyptian history. After her death, Nefertiti was buried in a rock-cut tomb in the Valley of the Kings and the Aten was passed down to Tutankhamun.
In 38 BCE, Nefertiti's tomb was pillaged by a group of tomb robbers, who stole a prized relic belonging to the pharaoh. When Nefertiti seemingly returned to the world of the living and plagued the city of Thebes, the residents of the city believed it was due to her tomb being disturbed. In reality, it was a result of the God's Wife of Amun, Isidora, who summoned the deceased pharaohs using an Apple of Eden that was once wielded by Nefertiti.
Irsu, the tomb robber who found the relic, intended to auction it on a small island for large sums of money. However, his nephew, Sutekh, who believed that returning the relic would appease Nefertiti, sabotaged the auction and took the relic for himself. While his uncle was captured and brought to the Temple of Hatshepsut, Irsu travelled to the village of Set-Ma'at, where he was ambushed by a group of bandits. Later assisted by the Hidden One Bayek of Siwa, Irsu gave the relic to Bayek who then travelled to Nefertiti's tomb in the valley.
While in the tomb, Bayek discovered a portal to the afterlife of Aaru, where Nefertiti's spirit resided in. Arriving at a temple dedicated to her, Bayek summoned the Nefertiti's spirit by fitting her relic into the throne. With Nefertiti's spirit summoned, Bayek fought and defeated her, allowing the Pharaoh to rest peacefully.
- Her name translates to Beautiful are the Beauties of Aten, the Beautiful one has come.