Nebefer was a new resident of Letopolis who moved in sometime in 48 BCE. Like other settlers, among them Nehi, she had found old hieroglyphs in her chosen home. At one point, Nebefer was visited by the Medjay Bayek of Siwa, who was attempting to solve the mystery behind the hieroglyphs. Nebefer told Bayek what she knew and asked him to help her pass a message to Nehi, asking how he was doing. Later on, Nebefer visited Nehi's home to have a meal with him.
After Bayek told Nehi what he'd discovered about the hieroglyphs, Nehi wondered if Nebefer would share his plans of leaving.