Ficino worked under the patronage of Lorenzo de' Medici, the leader of Florence. Known as a freethinker, he associated with Lorenzo at the latter's Villa Careggi. He also translated the writings of Hermes Trismegistus.
- Assassin's Creed: Renaissance (mentioned only)
- Assassin's Creed: Brotherhood – The Da Vinci Disappearance (mentioned only)