- "Calmatevi. The pain will end soon."
- ―Margherita whilst treating Ezio Auditore's injuries.[src]
Caring for Ezio
In January 1500, the Assassin Niccolò Machiavelli took Ezio Auditore da Firenze to Margherita's house in the northern Campagna District, where he could recover from the wounds he had sustained from arquebusiers during the siege of Monteriggioni.
- Margherita's name is only mentioned in the novelization of Assassin's Creed: Brotherhood.
- Despite being a noblewoman, Margherita did not appear to be wealthy or own a large property. This was most likely due to the Borgia's oppression.
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