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The Madiama Nome was a nome of Egypt situated on the Sinai, south of the Klysma Nome. A desolute land containing various oases, the nome provided respite for the nomadic Nabateans.

In 38 BCE, the Hidden One, Bayek, travelled to the region to hunt down Ampelius, a member of the Order of the Ancients, who fortified himself in the Walls-of-the-Ruler.

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