After receiving information that the Assassins were after the Scepter of Aset, Alan Rikkin met with Laetitia and Mitsuko Nakamura in New York, to ask them what should they do with the information. Mitsuko believed it was a trap and advised caution, but Laetitia thought they should do the opposite and act as quickly as possible. Rikkin considered both sides and assigned Vernon Hest to the mission, considering him one of their most careful and effective agents. Laetitia became Hest's contact.
Later on, Rikkin reassigned Laetitia to Project Hydra, and was present when Doctor William McCoy introduced them to Subject 19. William brought her up to speed about the project and they worked together for a while. Disappointed about Hest's progress on his mission, Rikkin pressured Laetitia on her project and discover the location of the Scepter as quickly as possible. After the memories of El Cakr became a dead end, Laetitia asked William to put Subject 19 into the Animus and discover the location of the Scepter through Leila's memories. After she got what she needed, Laetitia cut off Mike's oxygen.