- "Sic semper tyrannis!"
- ―John Wilkes Booth after assassinating Abraham Lincoln, 1865.[src]
In April 1865, with the Confederate Army losing the American Civil War, Booth planned the murder of President Lincoln along with several other political figures. However, only Booth was successful, shooting Lincoln in the back of the head before fleeing the scene.
- Booth once portrayed the Roman general Marcus Antonius in a production of Shakespeare's Julius Caesar; additionally, his father and brother, both fellow actors, were both named Junius Brutus, after Caesar's assassin.
- Assassin's Creed II (Glyphs only)