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"The blood flowing through you has the power to raze kingdoms, to alter the course of entire civilizations... You could burn this world."
―Pactyas the Huntsman on the possible powers of hyrbids, c. 429 BCE.[src]-[m]

The hybrids[1] were a humanoid species directly descended from those Isu who chose to interbreed with their human workforce. As a result of this interbreeding, hybrids were born without the artificial neurotransmitters that forced humanity's subservience to their Piece of Eden-wielding Isu overlords.


The only known hybrids, whose ability to disobey the commands of the Isu led to the outbreak of war in 75,010 BCE, were Adam and Eve.[2]

Over the subsequent generations, the hybrids and their offspring were assimilated into the general human population. Consequently, the concentration of Isu DNA in their own genome became diluted with each generation.

During the 5th century BCE, the Order of the Ancients started referring to humans directly descended from the hybrids—and as such, the Isu—who possessed extraordinary skills and abilities with the epithet "Tainted Ones", despising these traits and considering such individuals as being "less than human".[3]

In Ancient Greece, some such individuals were recognized by the greater human population and believed to be direct descendants of the gods.[4] Because of this, individuals like Kassandra and Alexios were often referred to as a "demigod", and revered as such by people like the Worshippers of the Bloodline, a branch of the Cult of Kosmos.[4]

Certain bloodlines directly descended from the hybrids, however, possessed fractionally higher levels of Isu DNA in their genome, resting somewhere between the 0.0002% to 0.0005% of normal humans and the 5 or 6% of Sages,[5] which allowed their scions to naturally access Eagle Vision and to more fully interact with Pieces of Eden much like their ancestors. In the case of Sages, their high Isu DNA count meant that they could serve as a reincarnation of Aita or a member of either the Æsir or Vanir, two Isu groups who once lived together in Asgard.

Considering the abilities of people like Kassandra and the knowledge and abilities shown by the Sages, Adam and Eve were most likely extremely physically and mentally powerful. In the video file titled "The Truth", Adam and Eve were shown freerunning from ground level to the top of Eden extremely quickly.[2]

Known Hybrids

Known "Tainted Ones"