Heliopolis was a major city of ancient Egypt.
In around 47 BCE, after arriving in the harbors of the Ptolemaic Royal Palace in Alexandria, Apollodorus posed as a Phylakitai of Heliopolis while carrying Cleopatra wrapped in a rug, with Aya and Bayek posing as his servants.
- The city does not make an appearance in the game, despite being mentioned.
- Heliopolis is also regarded as the most prominent place of worship of the goddess Sheshat.
- Assassin's Creed: Origins (mentioned only)