- "A dark tide rises to the east – an army of such size and power that all the land is made quick to worry. Their leader is a man named Temujin, who has adopted the title Genghis Khan. He sweeps across the lands, conquering and subsuming all who stand in his way."
- ―Altaïr Ibn-La'Ahad's Codex, page 29.[src]
Genghis Khan (Mongolian: ᠴᠢᠩᠭᠢᠰ ᠬᠠᠭᠠᠨ; c. 1162 – 1227), born Temüjin (Mongolian: ᠲᠡᠮᠦᠵᠢᠨ) was the founder and first emperor of the Mongol Empire, which he ruled from 1206 until his death.
By the year 1217, the Mentor of the Levantine Brotherhood of Assassins, Altaïr Ibn-La'Ahad, correctly suspected that Genghis Khan's rise to power was due in part to a Sword of Eden. Thus, Altaïr, his wife Maria, and his son Darim traveled to Mongolia intending to assassinate Khan and retrieve the Piece of Eden. In 1227, they located Genghis Khan in Xingqing around the time his forces were besieging the city; the Mongolian Assassin Qulan Gal shot Genghis Khan's horse with an arrow, dismounting the Mongol Emperor and providing Darim the chance to kill him with a crossbow bolt.
- Assassin's Creed: The Secret Crusade (first appearance)
- Assassin's Creed: Revelations (mentioned only)
- Assassin's Creed: Memories
- Assassin's Creed: Last Descendants – Tomb of the Khan (mentioned only)
- Assassin's Creed: Reflections