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First Do No Harm was a virtual representation of one of Kassandra's genetic memories, relived by Layla Hassan in 2018 through the Portable Animus HR-8.5.
Description
Kassandra travelled to Argos to look for Hippokrates, a healer whom she heard may have information on her mother's whereabouts.
Dialogue
The Adrestia docked at Epidauros, whereupon Kassandra made her way to Argos to talk with Hippokrates. Once in the city, she used Ikaros to identify his clinic.
- Kassandra: That's Hippokrates' clinic.
Upon reaching her destination, however, she discovered that Hippokrates was not there. Instead, an older woman and a young man were arguing.
- Chrysis: Apollo himself should smite your precious Hippokrates!
- Sostratos: But priestess, Hippokrates does respect Apollo.
- Chrysis: What an outrageous claim! Your words are daggers thrust into the heart of our faith. Do you want to bring ruin to all of Argolis?
- Sostratos: Of course not, but...
- Chrysis: Then tell me where to find Hippokrates!
- Sostratos: Forgive me, but I really can't help you.
Kassandra approached them as they continued to exchange words.

Chrysis threantening Sostratos
- Chrysis: Look, you insignificant peon. Tell me where he is or by Hera, I'll burn this clinic to the ground with you in it!
- Sostratos: I already told you what I know!
- Chrysis: I don't ask much. Hippokrates must show humility to ensure public order—prostrate himself before the gods, and declare that his skills are gods-given.
- Sostratos: But that won't help his patients. It'll just take him away from his work.
- Chrysis: If Hippokrates thinks he can disrupt social order to make himself into a demigod of healing... Well, perhaps the gods themselves will have their revenge.
- Kassandra: I'm sure there's no need for raised voices.
- Chrysis: Who are you?
- Kassandra: I'm looking for a man named Hippokrates.
- Chrysis: Yet another crazed follower of the madman himself! Tell your impious master that unless he makes a public apology and soon, this Priestess of Hera will gather an army of faithful and shut him down. Out of my way.
Chrysis stormed off.
- Sostratos: Oh, thank all the gods she's gone. I thought she was going to kill me this time.
- Kassandra: What's going on?
- Sostratos: I'm Sostratos. Chrysis has accused my master Hippokrates of impiety.
- Kassandra: Is he impious?
- Sostratos: He believes that beyond praying, people can take their health into their own hands and make themselves well.
- Kassandra: Fascinating. Can I speak with him?
- Sostratos: I'm sorry. He isn't here.
(If "Where is Hippokrates?" was chosen.)
- Kassandra: I need to meet Hippokrates. Is he in Argolis, at least?
- Sostratos: Yes, but he's gone southeast of Hera's Watch to help the sick and injured.
(If "What is this place?" was chosen.)

Hippokrates' clinic
- Kassandra: Is this his workshop?
- Sostratos: It's Hippokrates's clinic. Here we study healing, offer treatments, and provide care to anyone who asks.
- Kassandra: Why not work with the priests in the Sanctuary of Asklepios? It's what this region is known for, right?
- Sostratos: The priests try their best, but their methods are stuck in the past. Hippokrates is researching new cures and treatments.
(If "I need to find Hippokrates." was chosen.)
- Kassandra: I'll find him.
- Sostratos: If you're going to meet Hippokrates...could I trouble you with a small errand?
- Kassandra: Depends what it is.
- Sostratos: I want you to bring him some equipment. He was in such a hurry, he left it behind.
(If "What about your equipment?" was chosen.)
- Kassandra: What kind of equipment?
- Sostratos: Just medical necessities. Knives and gut for sutures, bandages... Oh, and an enema bag for clearing the bowels.
- Kassandra: They had better be properly wrapped.
(If "I think I can help you." was chosen.)
- Kassandra: I could bring that to Hippokrates.
- Sostratos: Really?
- Kassandra: My services don't come free.
Sostratos handed her a pouch of drachmae.
- Sostratos: Here, take this. Though perhaps Hippokrates can teach you something about helping those in need when you speak with him.
Kassandra traveled to the Cave of Pan.
- Kassandra: So many sick people... Can one man help all of them? I thought they were exaggerating when they said people from all around came to see Hippokrates.

Kassandra observing Hippokrates at work
She found Hippokrates tending to one of his patients.
- Kassandra: So, what has caused this man's condition?
- Nurse: An excess of phlegm, doctor.
- Hippokrates: In the immediate sense, yes. But more importantly, he suffers from neglect.
- Nurse: Neglect?
- Hippokrates: Good food, warm clothing, so much could have helped. But since other "caretakers" assumed his condition was a punishment from the gods, they neglected him.
- Kassandra: Challenging tradition... You must be Hippokrates.
- Hippokrates: Yes. I'm also very busy.
- Kassandra: Of course I did. I'm a misthios.
- Hippokrates: Ungenerous, but honest at least. What can I call you, misthios?
- Kassandra: I've been searching for a Spartan woman.
- Hippokrates: What makes you think I would know her?
- Kassandra: I was told you may have helped her a long time ago.

Kassandra meets Hippokrates
- Hippokrates: Maybe the priests at the Sanctuary of Asklepios can help. They keep detailed records of all who pass through.
- Kassandra: Please, Hippokrates. I came very far to meet you.
- Hippokrates: As did this patient, and the one before him, and the one before her. My patients need me, but my notes on diseases of the mind were taken. Retrieve them, and I will help you find what you seek. Hurry! This patient doesn't have much time left.

Hippokrates discussing the patient's condition
(If "Sostratos said not to mention you're balding." was chosen.)
- Kassandra: According to Sostratos, you don't like people mentioning your... you know.
- Hippokrates: My what?
- Kassandra: Your hair. Or lack of it.
- Hippokrates: Yes, yes. Make your jokes while walking around like one of Phidias' sculptures come to life.
(If "Where do you think your notes are?" was chosen.)
- Kassandra: Where should I look for your notes?
- Hippokrates: Fort Tiryns, not far from here. Perhaps they'll return them if you ask.
- Kassandra: Or they could prepare for a new battle, with me.
- Hippokrates: Far be it from me to tell a misthios how to work, but please, for my sake, do not kill needlessly. Enough blood has been shed in this war.
(If "Was it Chrysis who took your notes?" was chosen.)
- Kassandra: Did Chrysis take your notes?
- Hippokrates: Ah, you've met the priestess. No, not her, but the local military commander. I can't fault his desperation. Those men suffer terribly from battle fatigue.
(If "Why would the woman I'm after go to the sanctuary?" was chosen.)
- Kassandra: She would have come here a long time ago, with an injured baby. Are you sure she would have passed through the Sanctuary of Asklepios?
- Hippokrates: I was a young man then. When I encountered a situation beyond my skills, I would send the patient to the Sanctuary.
- Kassandra: And these priests kept records of their patients?
- Hippokrates: Yes, engraved in stone. The elder priest might remember.

Kassandra discussed and accepted Hippokrates' request
(If "What are the notes about?" was chosen.)
- Kassandra: What was so interesting about these notes?
- Hippokrates: They were my notes about diseases of the mind, including what the priests call the "Sacred Disease." That's what this patient has. He's losing control of his limbs and throat—sometimes frothing at the mouth. I fear his breathing will stop next.
(Leave – "I'll go.")
- Kassandra: I'll do my best with what you've told me.
- Hippokrates: Good luck. We're depending on you.
Outcome
Kassandra travelled to Hippokrates' clinic in Argos, meeting his apprentice Sostratos and an elderly priestess named Chrysis who had a beef with Hippokrates. Kassandra was directed to find Hippokrates at the Cave of Pan and deliver some equipment for him. After their meeting, Hippokrates asked Kassandra to recover his notes from a fort in exchange for what information she needed.
Gallery
Behind the scenes
Although it is not indicated as such, this quest is the first in a series that ultimately can result in players recruiting Hippokrates aboard the Adrestia towards the end of Assassin's Creed: Odyssey. However, it is very easy to immediately fail this goal because unlike Kassandra's dialogue choices in attempting to turn Deimos away from the Cult of Kosmos, Hippokrates' potential fate is decided by optional dialogues that are not indicated as being of high importance to the main plot's ending.
In this memory, having Kassandra ask Hippokrates about his baldness—despite Sostratos explicitly telling her not to mention it—will instantly render him ineligible to recruit later, leaving players unable to do so unless they load an earlier save from before they talked to him. Asking for pay and brushing off his statement that he is busy will also have the same result. The Assassin's Creed Odyssey: Official Game Guide also strongly suggests to avoid these options in favor of having Kassandra help the needy without thought of reward and quickly present her case to let Hippokrates return to work, although its decision is for the main plot and is based more on moral grounds than the desire to get the doctor aboard the ship.