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The Cien Ojos was a gang which Luis built up along with other young orphans of Madrid. However, as they targeted the Spanish Inquisition, more specifically a villa belonging to a Templar, the gang was utterly destroyed, leaving Luis as the sole survivor.
Behind the scenes
The gang shares its name, albeit in a different language, with the Cento Occhi of Assassin's Creed: Brotherhood. The leaders of the two gangs, Luis for the Cien Ojos and Lanz for the Cento Occhi, are also strikingly similar.