The Castillo de la Mota (English: Castle of the Butte) is a fortress in Medina del Campo, Spain, where it dominates the plateau, or butte, it is situated on. Initial fortification of the village, repopulated after Moorish depredations, led to the creation of a fortress on the site, starting in 1080. The village soon grew alongside.
From 1504 to 1506, following his attempted escape from the Castel Sant'Angelo, the Castillo de la Mota acted as a prison for Cesare Borgia. Cesare's location was kept a closely guarded secret between Pope Julius II and King Ferdinand II of Aragon; not even Ezio Auditore da Firenze, Mentor of the Italian Assassins, was allowed to know of Cesare's whereabouts.
Eventually, Cesare escaped the castle with aid of his lieutenant Micheletto Corella and a bribed prison guard. Having had rope smuggled in for him, Cesare climbed down from his window and snuck past the main gate in his stolen guard uniform. Not long after his escape, the Assassins Ezio Auditore, Niccolò Machiavelli and their friend Leonardo da Vinci arrived at the fortress in pursuit of Micheletto, only to learn of Cesare's escape.