Arch Enemies was a virtual representation of one of Ezio Auditore da Firenze's genetic memories, relived by Desmond Miles in 2012 through the Animus.
Description
Ezio Auditore received a contract from Lorenzo de' Medici to assassinate several Borgia archers stationed in Forlì, before they could endanger the city.
Outcome
Ezio tracked down and assassinated all of the targets, completing the contract.