Antonio Vespucci was a Florentine nobleman during the 15th century.
Father to one of the most beautiful women of her age, Cristina, Antonio was incensed by the nighttime visits of Cristina's lover, Ezio Auditore. Although he called guards on Ezio, they were never able to outmatch his speed and dexterity. Due to Antonio's adoration for his daughter, Cristina would often use her influence on him to ensure that Ezio would not suffer for his involvement with her.
In December 1476, Ezio was forced to leave Florence and Cristina, and Antonio began to insist his daughter choose what kind of life she wanted, and to choose a husband. She eventually married Manfredo Soderini.