If this franchise ends, how do you guys want the last game to be??
Spoiler for people who haven't played till Ac3!!!
Juno takes over the world through the body of Abstergo CEO. Desmond will not be dead and is imprisoned by Abstergo at their headquarters. A female character ( withe Eve lineage) should rescue Desmond who now enters the animus and re-lives the memories of all assassin's so far with each chapter dedicated to all assassin (so far played by us) who hide a part of very powerful PoE which has the power to kill Juno(or any other Isu). And finally modern assassin's assemble all the parts and solve the puzzle to obtain the PoE. with that Desmond enters Abstergo headquarters where he has to kill all the guards stealthily (assassin's way) . And finally there will be boss battle against Juno and Desmond kills Juno eliminating the global threat. With the most powery PoE with assassin's they throw assassin's out of power and destroys all animus projects.
As the end credits role, Desmond heads to secret vault where he enter animus, closes his eyes and a Flash!!!