Michelangelo

Michelangelo di Lodovico Buonarroti Simoni (6 March 1475 – 18 February 1564), commonly known as Michelangelo, was an Italian Renaissance painter, sculptor, architect, poet, and engineer. Michelangelo's skill was of such a high order that he is often considered a contender for the title of the archetypal Renaissance man, along with his rival and fellow Italian Leonardo da Vinci.

Cameo in Assassin's Creed II
Michelangelo wrote a letter to his father, in which he states that he wants to live up to his father's expectations, but also wants to be an artist, a job his father does not approve. The letter was delivered to his father by Ezio Auditore da Firenze, who acted as mailman.