User blog comment:Master Sima Yi/"World War II not unlikely for AC III."/@comment-5919381-20101013113539/@comment-1153722-20101013114846

I can't see a female Assassin working either. If they want a female Assassin, I guess they should start a whole new storyline with a female descendant.

And I don't believe the Feudal Japan thing would work out too well neither, as it takes place almost right after the events of Assassin's Creed: Brotherhood. A more logical time period would be the 17th or 18th century.