Assassination target

"Find them, kill them. In doing so, you will sow the seeds of peace."

- Al Mualim conversing about assassination targets with Altaïr, 1191.

Assassination targets were individuals that the Assassin Order – and in select instances, the Templar Order – deemed worthy of elimination. Over the centuries, the Assassins killed many individuals they believed to be corrupt and a danger to humanity, particularly Templars and their associates.

Below is a chronological list of notable victims, by faction and assassin responsible.

Altaïr Ibn-La'Ahad
Around the time of the Third Crusade, Altaïr Ibn-La'Ahad assassinated various individuals during his quest to find the Chalice in 1190. He later eliminated nine tyrannical public figures in an effort to restore his lost rank and regain honor within the Assassin Order.

Following his ascension to Mentor of the Order, he carried out several assassinations to aid the Cypriot Resistance in 1192, and continued to eliminate notable targets throughout his life.

1189 – 1190= 1191= 1192 – 1193= 1227 – 1247=
 * Haras – 1189
 * Tamir of Damascus – 1190
 * Alaat – 1190
 * Firas –1190
 * Roland Napule – 1190
 * The Master's Student – 1190
 * Master of the Tower – 1190
 * Harash – 1190
 * Lord Basilisk – 1190
 * Tamir
 * Garnier de Naplouse
 * Talal
 * Abu'l Nuqoud
 * William of Montferrat
 * Majd Addin
 * Sibrand
 * Jubair al Hakim
 * Robert de Sablé
 * Rashid ad-Din Sinan
 * Emin
 * Frederick the Red
 * Moloch – 1192
 * Dark Oracle – 1192
 * Telemachos – 1192
 * Shalim – 1192
 * Shahar – 1192
 * Pirate Captain – 1193
 * Armand Bouchart – 1193
 * Swami – 1227
 * Bayhas – 1247
 * Abbas Sofian – 1247

Ezio Auditore da Firenze
During the Renaissance, the Assassin Ezio Auditore da Firenze eliminated various individuals in order to avenge the death of his family members, free the Spanish Assassins, and liberate the Italian city-states – Florence, San Gimignano, Forlì, Venice and Rome – as well as the Ottoman city of Constantinople and Byzantine underground outpost of Derinkuyu from corruption.

1476 – 1479= 1480 – 1489= 1490 – 1499= 1500 – 1509= 1511 – 1512=
 * Uberto Alberti – 1476
 * Vieri de' Pazzi – 1478
 * Francesco de' Pazzi – 1478
 * Antonio Maffei – 1478
 * Francesco Salviati – 1479
 * Bernardo Baroncelli – 1479
 * Stefano da Bagnone – 1479
 * Jacopo de' Pazzi – 1480
 * Emilio Barbarigo – 1485
 * Carlo Grimaldi – 1485
 * Marco Barbarigo – 1486
 * Silvio Barbarigo – 1486
 * Dante Moro – 1486
 * Ludovico Orsi – 1488
 * Checco Orsi – 1488
 * Gaspar Martínez – 1491
 * Pedro Llorente – 1491
 * Juan de Marillo – 1492
 * The Painter – 1497
 * The Guard Captain – 1497
 * The Nobleman – 1497
 * The Priest – 1497
 * The Merchant – 1497
 * The Doctor – 1497
 * The Farmer – 1497
 * The Condottiero – 1497
 * The Preacher – 1497
 * Girolamo Savonarola – 1498
 * Il Carnefice – 1500
 * Iacopo de Grassi – 1500
 * Belardino da Verona – 1500
 * Prospero da Siena – 1500
 * Valentino da Siena – 1500
 * Tommaso di Viterbo – 1500
 * Pietro da Siena – 1500
 * Domenico da Padova – 1500
 * Francesco da Velletri – 1500
 * Master of the Sacred Palace – 1500
 * Battista Borgia – 1500
 * Malfatto, via an apprentice – 1502
 * Silvestro Sabbatini, via an apprentice – 1502
 * Luigi Torcelli – 1503
 * Juan Borgia the Elder – 1503
 * Lanz – 1503
 * Auguste Oberlin – 1503
 * Ristoro – 1503
 * Gaspar de la Croix – 1503
 * Lia de Russo – 1503
 * Donato Mancini – 1503
 * Charles de la Motte – 1503
 * Antonio da Fiorentino – 1503
 * Ferdinando di Napoli – 1503
 * Ippolito di Foligno – 1503
 * Octavian de Valois – 1503
 * Ercole Massimo – 1506
 * Cesare Borgia – 1507
 * Leandros – 1511
 * Halim – 1511
 * Vali cel Tradat, via an Apprentice – 1511
 * Cyril of Rhodes – 1511
 * Mirela Djuric – 1511
 * Georgios Kostas, via an Apprentice – 1511
 * Odai Dunqas, via an Apprentice – 1511
 * Damat Ali Pasha, via an Apprentice – 1511
 * Lysistrata – 1511
 * Tarik Barleti – 1511
 * Shahkulu – 1512
 * Manuel Palaiologos – 1512

Shao Jun
After the Great Rites Controversy which resulted in the decimation of the Chinese Assassins at the hands of the Eight Tigers, Shao Jun assassinated the Templars responsible in a campaign to free China and restore the Chinese brotherhood.

1526 – 1532=
 * Gao Feng – 1526
 * Yu Dayong – 1526
 * Wei Bin – 1529
 * Qiu Ju – 1530
 * Zhang Yong – 1532

Edward Kenway
Edward Kenway assassinated several individuals during the Golden Age of Piracy in his quest for riches and glory as a pirate, and later in service of the Assassin Order.

1712 – 1719= 1721 – 1723=
 * Julian – 1712
 * Duncan Walpole – 1715
 * Julien du Casse – 1715
 * Vargas – 1716
 * Lucia Márquez – 1716
 * Kenneth Abraham – 1716
 * Juan Garcia – 1716
 * Trevor – 1716
 * Antonio Rueda – 1716
 * Mancomb Seepgood – 1716
 * Arispe – 1716
 * Laurens Prins – 1717
 * Hilary Flint – 1717
 * Vance Travers – 1717
 * Jing Lang – 1717
 * Wyatt – 1718
 * Peter Chamberlaine – 1718
 * Josiah Burgess – 1719
 * John Cockram – 1719
 * Benjamin Hornigold – 1719
 * Ruggiero Ferraro – 1721
 * Bartholomew Roberts – 1722
 * El Tiburón – 1722
 * Laureano de Torres y Ayala – 1722
 * Emmett Scott – 1723
 * Wilson – 1723

Adéwalé
During the early 18th century, Adéwalé served as quartermaster on Edward Kenway's ship before eventually joining the Assassin Brotherhood and assuming the captaincy of his own vessel.

In 1735, he briefly set aside his duties as an Assassin in order to aid the Maroon rebellion in Saint Domingue.

1735 – 1737=
 * Templar Admiral – 1735
 * Pierre, Marquis de Fayet– 1737

Aveline de Grandpré
Aveline de Grandpré assassinated various targets between the French and Indian War and American Revolutionary War in an effort to free New Orleans from Templar influence and liberate victims of the slave trade.

1765 – 1769= 1771 – 1784=
 * Jean-Jacques Blaise d'Abbadie – 1765
 * Baptiste – 1766
 * Ratel – 1768
 * Reynaud – 1768
 * De Vandal – 1768
 * Rafael Joaquín de Ferrer – 1769
 * Salmon – 1771
 * Marcantell – 1771
 * Chapperon – 1771
 * De Chevallier – 1771
 * Bouché – 1771
 * Diego Vázquez – 1776
 * George Davidson – 1777
 * Madeleine de L'Isle – 1777
 * Edmund Judge – 1784

Ratonhnhaké:ton
Before, during, and after the events of the American Revolutionary War, the Assassin Ratonhnhaké:ton, son of the Templar Haytham Kenway and grandson of pirate turned Assassin Edward Kenway, eliminated various Templars in order to protect his tribe and further the pursuit of freedom for the citizens of the thirteen colonies of the United States.

Following a meeting with George Washington, Ratonhnhaké:ton found himself in an alternate reality created by an Apple of Eden. There, he assassinated several individuals while experiencing the alternate timeline.

1774 – 1779= 1780 – 1782= Alternate reality=
 * William Johnson – 1774
 * John Pitcairn – 1775
 * Thomas Hickey – 1776
 * Man O' War captain – 1776
 * Benjamin Church – 1778
 * Nicholas Biddle – 1778
 * Haytham Kenway – 1781
 * Charles Lee – 1782
 * Benedict Arnold
 * Israel Putnam
 * John Fitzwilliams
 * George Washington

Arno Dorian
Following the death of his adoptive father, the Templar Grand Master François de la Serre, Arno Dorian joined the Assassin Brotherhood and embarked on a quest to find the perpetrators of the murder and their motivations.

While pursuing his own agenda, Arno also undertook several missions in order to thwart the efforts of the Templars, who tried to take control of the French Revolution.

1791 – 1794= 1794 – 1800=
 * Duchesneau – 1791
 * Charles Gabriel Sivert – 1791
 * Roi des Thunes – 1791
 * Chrétien Lafrenière – 1791
 * Pierre Bellec – 1791
 * Flavigny – 1792
 * Comte de Gambais – 1792
 * Vicomte de Gambais – 1792
 * Frédéric Rouille – 1792
 * Renard – c. 1792
 * Marie Lévesque – 1792
 * Comte de Choisy – c. 1793
 * Crimson Rose – c. 1793
 * Louis-Michel le Peletier – 1793
 * Aloys la Touche – 1793
 * Marcourt – 1793
 * Jean Gilbert – 1793
 * Jacques Roux – 1794
 * Jacques Roux's lieutenant – 1794
 * Jean Lessard – 1794
 * Andrés de Guzmán – 1794
 * François-Thomas Germain – 1794
 * Philippe Rose – 1794
 * Jean-Baptiste Rotondo – 1795
 * François-Joseph Carbon – 1800

Arbaaz Mir
In 1841, two years after the events that led to the death of Maharaja Ranjit Singh and while India was in the midst of a war between the Sikh Empire and the East India Company, Arbaaz Mir began a race with the Templars to recover the famed Koh-i-Noor diamond.

1841 – 1856= 1856 – 1860=
 * Alexander Burnes – 1841
 * William Sleeman – 1856
 * Tjinder Dani‎ – 1860

Jacob & Evie Frye
The twins Jacob and Evie Frye where active in London and its surrounding areas in 1868 as the Industrial Revolution reached its climax. Here they fought against the inequality and poverty engineered by the Templars, taking over organized crime in the city in an effort to destabilize the Templar's hold over it and stop them from acquiring a powerful Piece of Eden.

1868= Jacob's targets: Evie's targets: Unknown:
 * Rupert Ferris
 * John Elliotson
 * Malcolm Millner
 * Pearl Attaway
 * Philip Twopenny
 * James Brudenell, 7th Earl of Cardigan
 * Maxwell Roth
 * Crawford Starrick
 * David Brewster
 * Lucy Thorne
 * Crawford Starrick
 * Henry Raymond
 * Rexford Kaylock
 * Argus Bartlett
 * Rose Bartlett
 * Phillip Beckenridge
 * Thomas Blackroot
 * Louis Blake
 * Bloody Nora
 * Wallace Bone
 * Charlie
 * Eveline Dipper
 * Tom Eccleston
 * Martin Church
 * Ada Cobleigh
 * Clyde Cobleigh
 * Edgar Collicott
 * Harold Drake
 * Francis Fletcher
 * Josephine Fletcher
 * Lilla Graves
 * Beatrice Gribble
 * Samuel Hargrave
 * Kent Jekyll
 * Raphael Jekyll
 * Victor Lynch
 * Peter Needham
 * Big Pete
 * Myrtle Platt
 * Octavia Plumb
 * Cletus Strain
 * Edith Swinebourne

Lydia Frye
During World War I, Lydia Frye allied herself with Winston Churchill to take down a German-Templar spy network led by a Sage. 1916=
 * Magpie
 * Nurse
 * Nurse's accomplice
 * Master Spy

Nikolai Orelov
During the Russian Revolution, Nikolai Orelov served his Order faithfully, rising to the rank of Master Assassin before growing disillusioned and leaving the order. 1917=
 * Khioniya Guseva

Desmond Miles
Following his kidnapping by Abstergo Industries and training with the Assassins, Desmond Miles was forced by Juno to assassinate Lucy Stillman in the Colosseum Vault for her secret defection and betrayal. He later infiltrated the Abstergo Industries headquarters in Rome and assassinated two prominent members of their Order.

2012=
 * Lucy Stillman
 * Daniel Cross
 * Warren Vidic

Other Assassins
Below is a chronological list of other notable assassinations, by century and, if known, Assassin responsible:

BCE= 1st= 3rd= 12th= 13th= 14th= 15th= 16th= 18th= 19th= 20th= 21st=
 * Xerxes I of Persia, by Darius – 456 BCE
 * Alexander the Great, by Iltani – 323 BCE
 * Qin Shi Huang, by Wei Yu – 210 BCE
 * Gaius Julius Caesar, by Marcus Junius Brutus and others – 44 BCE
 * Cleopatra, by Amunet – 30 BCE
 * Caligula, by Leonius – 41
 * Titus, by Aquilus – 259
 * Caius, by Aquilus – 259
 * Faustinus, by Aquilus – 259
 * Caïus Fulvus Vultur, by Aquilus – 259
 * Masun, by Rashid ad-Din Sinan – 1191
 * Jochi Khan, by Qulan Gal and Darim Ibn-La'Ahad – 1227
 * Genghis Khan, by Qulan Gal and Darim Ibn-La'Ahad – 1227
 * Chagatai Khan, by Qulan Gal – 1241
 * Ögedei Khan, by Nergüi – 1241
 * Alexander Nevsky, by Nergüi – 1263
 * Hülegü Khan, by Nergüi – 1265
 * Benedict XI, by Guillaume de Nogaret – 1304
 * Jacques de Molay's advisor, by Thomas de Carneillon – 1307
 * Bachir Al-Djallil, by Numa Al'Khamsin – 1340
 * Yongle, by Li Tong – 1424
 * Vlad Tepes – 1476
 * Cem – 1495
 * Perotto Calderon – 1498
 * Tomás de Torquemada – 1498
 * Agostino Barbarigo, by Tessa Varzi – 1501
 * Cahin – 1503
 * Caha – 1503
 * Rocco Tiepolo – 1503
 * Baltasar de Silva – 1503
 * Margaret of York, – 1503
 * Isabella I of Castile – 1504
 * Niccolò di Pitigliano, by Francesco Vecellio – 1510
 * Francisco – 1511
 * Juan Ponce de León – 1521
 * Ma Yongcheng, by Wang Yangming – 1526
 * The Viper, by Giovanni Borgia – 1527
 * Francisco Pizarro – 1541
 * Mary I of England – 1558
 * Jiajing Emperor – 1567
 * Mōri Motonari, by Hattori Hanzō – 1571
 * Uesugi Kenshin, by Hattori Hanzō – 1578
 * Ivan Ivanovich of Russia – 1581
 * Oda Nobunaga, by Yamauchi Taka – 1582
 * Mochizuki Chiyome, by Hattori Hanzō – 1590s
 * Toyotomi Hideyoshi, by Yamauchi Taka – 1598
 * Shima Sakon, by Yamauchi Taka – 1600
 * Abel Bramah, by Duncan Walpole – 1715
 * Nāder Shāh, by Salah Bey – 1747
 * Lawrence Washington, by Shay Cormac – 1752
 * Samuel Smith, by Shay Cormac – 1754
 * James Wardrop, by Shay Cormac – 1754
 * George Monro, by Liam O'Brien – 1757
 * Richard Montgomery – 1775
 * Johann Rall – 1776
 * Friedrich Baum – 1777
 * Carl Emilius von Donop – 1777
 * George Dorrance – 1778
 * John Boyd – 1779
 * Hugh Jackson – 1779
 * Johann de Kalb – 1780
 * Hector McNeill – 1781
 * Jonathan Trumbull – 1785
 * Arpinon, by Pierre Bellec – 1791
 * Honoré Gabriel Riqueti, comte de Mirabeau, by Pierre Bellec – 1791
 * Jeannot Bullet, by Eseosa – 1791
 * Charles Leclerc, by Eseosa – 1802
 * Robert Waugh, by Ethan Frye – 1862
 * Hardy, by Ethan Frye – 1862
 * Smith, by Ethan Frye – 1862
 * Other Hardy, by Jayadeep Mir – 1862
 * John Wilkes Booth – 1865
 * Alexander II of Russia – 1881
 * Dolinsky - 1908
 * Erich Albert – 1914
 * Adolf Hitler – 1945
 * Joseph Stalin – 1953
 * François Duvalier – 1971
 * Avdotya Voronina, by Galina Voronina – 2014
 * Galina Voronina's mother, by Galina Voronina – 2014
 * Isabelle Ardant, by Shaun Hastings – 2015

Haytham Kenway
Son of the Assassin Edward Kenway, Haytham was converted to the Templar cause at a young age by Reginald Birch. A member of the British Rite, he later became the Grand Master of the Colonial Rite.

1747 – 1755=
 * Juan Vedomir – 1747
 * Miko – 1754
 * Louis Mills – 1754
 * Cutter – 1754
 * Slater – 1754
 * Edward Braddock – 1755

Shay Cormac
Formerly a member of the Colonial Assassins, Shay Cormac later became a famous Assassin hunter after he joined the Templar Order, pursuing his former Assassin brothers and sisters.

1756 – 1760= 1776=
 * Le Chasseur – 1756
 * Kesegowaase – 1757
 * Adéwalé – 1758
 * Hope Jensen – 1759
 * Louis-Joseph Gaultier, Chevalier de la Vérendrye – 1760
 * Charles Dorian – 1776

Daniel Cross
Brainwashed from an early age by the Templar-led Abstergo Industries, Daniel Cross served as a sleeper agent inside the Assassin Order and betrayed them leading to the decimation of the Assassins. 2010-2012=
 * "The Mentor" – 2000
 * Hannah Mueller – 2011
 * Janice – 2012

Other Templars
Below is a chronological list of other notable assassinations, by century and, if known, Templar responsible:

3rd= 12th= 14th= 15th= 16th= 18th= 19th= 20th= 21st=
 * Lucius, by Caïus Fulvus Vultur – 259
 * Isaac Comnenus, by Armand Bouchart – c. 1191
 * Osman, by Armand Bouchart – 1191
 * Barnabas, by Armand Bouchart's agent – 1191
 * Demetris, by Armand Bouchart's agent – 1192
 * Alexander of Limassol, by Armand Bouchart's agent – 1193
 * Dante Alighieri – 1321
 * Marco Polo – 1324
 * Al-Nasir Muhammad, by Leila – 1341
 * Numa Al'Khamsin, by Leila - 1341
 * Galeazzo Maria Sforza, by Giovanni Andrea Lampugnani, Gerolamo Olgiati, Carlo Visconti – 1476
 * Giovanni Auditore da Firenze, Federico Auditore da Firenze, Petruccio Auditore da Firenze – 1476
 * Giuliano de' Medici, by Francesco de' Pazzi and Bernardo Baroncelli – 1478
 * Giovanni Mocenigo, by Carlo Grimaldi – 1485
 * Girolamo Riario, by Checco Orsi and Ludovico Orsi – 1488
 * Juan Borgia the Younger, by Fiora Cavazza – 1497
 * Mario Auditore, by Cesare Borgia – 1500
 * Ramiro d'Orco – 1500
 * Alfonso of Aragon, by Micheletto Corella – 1500
 * Giulio Cesare da Varano, by Micheletto Corella – 1502
 * Astorre III Manfredi, by Micheletto Corella – 1502
 * Oliverotto da Fermo, by Micheletto Corella – 1502
 * Vitellozzo Vitelli, by Micheletto Corella – 1502
 * Francesco Troche, by Micheletto Corella – 1503
 * Rodrigo Borgia, by Cesare Borgia – 1503
 * Micheletto Corella, by Cesare Borgia – 1506
 * Theodorus Komnenos, by Odai Dunqas – 1511
 * Yusuf Tazim – 1512
 * Zhu Jiuyuan – 1524
 * Wang Yangming, by Zhang Yong – 1529
 * Tom Cobleigh, by Wilson – 1713
 * Samuel Bellamy – 1717
 * Barnes, by Christopher Condent – 1717
 * Howell Davis – 1719
 * Edward Kenway, by mercenaries in the employ of Reginald Birch – 1735
 * Jack Digweed, by Reginald Birch – 1747
 * Vendredi, by Lawrence Washington – 1751
 * Silas Thatcher, by Benjamin Church – 1754
 * François Mackandal – 1758
 * Philippe de Grandpré, by Madeleine de L'Isle – 1776
 * Lucio Albertine – 1788
 * Monica Albertine – 1788
 * May Carroll, by Élise de la Serre – 1788
 * François de la Serre, by Charles Gabriel Sivert and Le Roi des Thunes – 1789
 * Hook, by Élise de la Serre – 1789
 * Harvey, by Élise de la Serre – 1789
 * Le Fanu – 1790
 * Élise de la Serre, by François-Thomas Germain – 1794
 * Bernard Ruddock, by Frederick Weatherall – 1794
 * Ranjit Singh, by Francis Cotton and William Hay Macnaghten – 1839
 * Walter Lavelle, by Cavanagh – 1850s
 * Charles Pearson, by Cavanagh – 1862
 * Cavanagh, by Marchant – 1862
 * Abraham Lincoln, by John Wilkes Booth – 1865
 * Harry Houdini – 1926
 * Mahatma Gandhi – 1948
 * Harry Dexter White – 1948
 * Jack Parsons – 1952
 * Alan Turing – 1954
 * John F. Kennedy, by Lee Harvey Oswald – 1963
 * Subject 15 – 2010
 * Siobhan Dhami, by a special ops team led by Juhani Otso Berg – 2013
 * Dinesh, by a special ops team led by Juhani Otso Berg – 2013
 * Robert Fraser – 2014
 * Victoria Bibeau – 2014

Survivors
In carrying out their missions, some Assassins notably spared potential victims, or otherwise did not complete an assassination as directed. The following is a chronological list of targets known to have survived encounters with Assassin or Templar attackers:


 * Maria Thorpe – spared by Altaïr Ibn-La'Ahad, 1191
 * Ezio Auditore da Firenze – failed by Templars, during the 15th and the 16th centuries
 * Tomás de Torquemada – escaped from Ezio Auditore da Firenze, 1492
 * Rodrigo Borgia – spared by Ezio Auditore da Firenze, 1499
 * Micheletto Corella – spared by Ezio Auditore da Firenze, 1503
 * Vali cel Tradat - escaped an attack from Ezio Auditore da Firenze and one of his recruits, 1511
 * Cyril of Rhodes - escaped an attack from Ezio Auditore da Firenze and one of his recruits, 1511
 * Lysistrata - escaped an attack from Ezio Auditore da Firenze and one of his recruits, 1511
 * Mirela Djuric - escaped an attack from Ezio Auditore da Firenze, one of his recruits, and a trio of Romani, 1511
 * Georgios Kostas - escaped an attack from Ezio Auditore da Firenze and one of his recruits, 1511
 * An unspecified Ottoman Assassin - survived an ambush by Georgios Kostas, 1511
 * Charles Vane – spared by Edward Kenway, 1719
 * Woodes Rogers – survived attack by Edward Kenway, 1721
 * Matthew Hague – spared by Edward Kenway, 1723
 * Shay Cormac – failed by Assassins, between 1756 and 1760
 * Achilles Davenport – spared by Haytham Kenway, 1760
 * Antonio de Ulloa – spared by Aveline de Grandpré, 1768
 * Agaté – spared by Aveline de Grandpré, 1777
 * Benedict Arnold – failed by Ratonhnhaké:ton and Assassin apprentices, in 1780 and 1781
 * Benjamin Franklin – spared by Ratonhnhaké:ton, in an alternate reality.
 * Roi des Thunes – escaped three assassination attempts, 1791
 * Jacques Roux – escaped an assassination attempt by three Assassins, 1794
 * Alexander III of Russia - survived an assassination attempt by the Assassin Nikolai Orelov in 1894.

Interceptions
On occasion, the Assassins and Templars saved individuals from being killed. The following is a list of targets, the individuals who wanted their death and the person that saved them:


 * Rashid ad-Din Sinan, Fahd El Fehmi, and Vahid Ahmedi – targeted by Haras, saved by Altaïr Ibn-La'Ahad, 1189
 * Richard I of England – targeted by William of Montferrat, saved by Altaïr Ibn-La'Ahad, 1191
 * Lorenzo de' Medici – targeted by Francesco de' Pazzi, saved by Ezio Auditore da Firenze, 1478
 * Rosa and Ugo - targeted by Emilio Barbarigo's guards, saved by Ezio Auditore da Firenze, 1480
 * Bianca Riario and Ottaviano Riario – targeted by Ludovico and Checco Orsi, saved by Ezio Auditore da Firenze, 1488
 * Luis Santangel, Raphael Sanchez and Christoffa Corombo – targeted by Templars, saved by Ezio Auditore da Firenze, 1492
 * Claudia and Maria Auditore da Firenze - targeted by Cesare Borgia, saved by Ezio Auditore da Firenze, 1500
 * Ezio Auditore da Firenze - targeted by Cesare Borgia, saved by Niccolò Machiavelli, 1500
 * Nicolaus Copernicus – targeted by Templars, saved by Ezio Auditore da Firenze, 1500
 * Desiderius Erasmus - targeted by Templars, saved by an Italian Assassin sent by Ezio Auditore da Firenze, 1500
 * Prospero and Fabrizio Colonna- targeted by Borgia guards and Templars, saved by Ezio Auditore da Firenze, 1500
 * Pantasilea Baglioni - targeted by Baron Octavian de Valois, saved by Ezio Auditore da Firenze, 1503
 * Pietro Rossi – targeted by Micheletto Corella, saved by Ezio Auditore da Firenze, 1503
 * Niccolò Machiavelli – targeted by La Volpe, saved by Ezio Auditore da Firenze, 1503
 * Claudia Auditore da Firenze – targeted by Templars, saved by Ezio Auditore da Firenze and Niccolò Machiavelli, 1504
 * Suleiman I – targeted by Byzantine Templars, saved by Ezio Auditore da Firenze and Yusuf Tazim, 1511
 * Pachomius I of Constantinople – targeted by Cyril of Rhodes, saved by Ezio Auditore da Firenze, 1511
 * Manuel Palaiologos, Shahkulu, and Byzantine soldiers - targeted by Tarik Barleti and Janissaries, accidentally saved by Ezio Auditore da Firenze, 1511
 * Dilara - targeted by Manuel Palaiologos and Shahkulu, saved by Ezio Auditore da Firenze, 1511
 * Janos and other Ottoman spies - targeted by Manuel Palaiologos and Shahkulu, saved by Ezio Auditore da Firenze and Dilara, 1512
 * Sofia Sartor and Azize - targeted by Ahmet, saved by Ezio Auditore da Firenze, 1512
 * Shao Jun – targeted by Imperial soldiers, aided by Ezio Auditore da Firenze, 1524
 * Bernard Kenway and Linette Kenway - targeted by Wilson, Tom Cobleigh and Julian, saved by Edward Kenway, 1712
 * Ah Tabai – targeted by Duncan Walpole, indirectly saved by Edward Kenway, 1715
 * Antó – targeted by Kenneth Abraham, saved by Edward Kenway, 1716
 * Opía Apito – targeted by Lucia Márquez, saved by Edward Kenway, 1716
 * Rhona Dinsmore – targeted by Hilary Flint, saved by Edward Kenway, 1717
 * Upton Travers – targeted by Vance Travers and Jing Lang, saved by Edward Kenway, 1717
 * Augustin Dieufort – targeted by Pierre, Marquis de Fayet, saved by Adéwalé, 1735
 * Louis Godin – targeted by pirates, saved by Adéwalé, 1736
 * Benjamin Church – targeted by Cutter, saved by Haytham Kenway and Charles Lee
 * David Borgen, Conan Brown, Michael Crawley, Randall Gordon, Franklin Greear, Maria Gurley, Lewis Johnson, Scott Lawson, Philippe Beaubien, Rachel Plourde, Kelly Snider – targeted by Assassins, saved by Shay Cormac, between 1756 and 1760
 * Ratonhnhaké:ton – targeted by Charles Lee, saved by Haytham Kenway, 1776
 * George Washington – targeted by Thomas Hickey, saved by Ratonhnhaké:ton, 1776
 * Benjamin Franklin – targeted by criminals, saved by Shay Cormac, 1776
 * Benjamin Franklin and Kanen'tó:kon – targeted by Israel Putnam, saved by Ratonhnhaké:ton, in an alternate reality
 * Élise de la Serre – targeted by Templars, saved by Arno Dorian, in 1791
 * Théroigne de Méricourt – targeted by Templars, saved by Arno Dorian, in 1789 and 1792
 * Georges Danton – targeted by Royalists, saved by Arno Dorian, 1792
 * Didier Paton – targeted by Maximilien de Robespierre, saved by Arno Dorian, 1794
 * Léon – targeted by Philippe Rose, saved by Arno Dorian, 1794
 * Napoleon Bonaparte – targeted by Royalists, saved by Arno Dorian, in 1795 and in 1800
 * Benjamin Disraeli and Mary Anne Disraeli – targeted by Blighters, saved by Jacob Frye, 1868
 * Lucy Stillman - targeted by Abstergo guards, saved by Warren Vidic, 2000s
 * William Miles – targeted by Daniel Cross and Warren Vidic, saved by Desmond Miles, 2012