Innocent VIII

Pope Innocent VIII (Latin: Innocentus VIII; 1432 – 25 July 1492), born Giovanni Battista Cybo, was Pope from 1484 to his death.

Following his death, the Templar Grand Master Rodrigo Borgia bribed several cardinals, and was elected as Pope Alexander VI. In 2012, the Assassin Shaun Hastings noted this, as his fellow Assassin Desmond Miles relived the memories of Ezio Auditore da Firenze, Borgia's arch enemy, through the Animus.

Reference

 * Assassin's Creed II