User blog comment:AED/Footprints in the Villa/@comment-4136895-20110711204854

I think it's Ezio in some way. The trail lead's to Mario's study which has the secret door containing: 1. The path to the sanctuary, and during the raid it was everyone's escape (including a bleeding Ezio) 2. The password to the vault where Ezio hid the Piece of Eden.