Fist

In the Assassin's Creed series, fists are the weakest form of fighting available to the player. Guards will not intervene with a fistfight, unless they themselves are attacked. However, if the player draws a weapon, they will intervene.

Third Crusade
In Assassin's Creed, Altaïr Ibn-La'Ahad can use his fists to fight or stun enemies at any time, though they are quite ineffective as the guards will still be using weapons. As a novice, they are the only form of combat he can use in a fight, though that is only for one mission. He mainly uses them in special situations, such as interrogating a target, or after being caught by a thug while attempting to pickpocket throwing knives, as drawing a weapon will cause them to flee.

Renaissance Italy (1476 - 1499)
In Assassin's Creed II, Ezio Auditore da Firenze is more skilled in fistfighting than his ancestor Altaïr. He can perform many different combination strikes, counter other fist fighters, throw sand in their faces, and eventually learn how to disarm foes and use their weapons. The special attack while unarmed is to lean down and sweep sand into the opponent's eyes, breaking their defences, thus opening them up for a quick attack or even kill. Fists also become a more viable tool for combat when the Metal Cestus, a hard steel hand-guard that strengthens the attack of the fists, becomes available for purchase from blacksmiths.

Renaissance Italy (1500 - 1507)
In Assassin's Creed: Brotherhood, Ezio is still able to disarm his opponents, but now has the added ability to kill them in one swift move by hitting them once more, thus performing a combination strike. This combination strike can also be done by simply hitting a guard, as long as he is not already in open combat. Guards can now also throw sand in Ezio's face, exactly as he can, but they do not require their hands to be free. However, Ezio can perform the same move with his weapon equipped, as long as he has no bullets or throwing knives left.

Modern Times
During the beginning and end of Assassin's Creed II, Desmond is able to fistfight Abstergo security officers. Though at the beginning, his abilities are rather slim, and is only able to perform basic moves, but once he has gained some of Ezio's skills through the bleeding effect, his fistfighting vastly improves, and he is now able to perform the more advanced techniques, such as disarming an enemy. As well as this, his ability to simultaneously use his newly acquired hidden blade resembles that of a highly trained Assassin. Desmond is Etzio's relitive that you are playing the game through.)

Stats
Without the Metal Cestus upgrade, Ezio's fists will only have 1 damage, 5 speed, and 1 counter. The Metal Cestus boosts the damage stat to three.

Trivia

 * In Assassin's Creed II, you earn the Achievement/Trophy, Messer Sandman, worth 10G or a Bronze Trophy, by using the sand throwing technique on four guards at once.
 * When Ezio picks up a body, the fists will automatically become selected.
 * When you successfully disarm a guard and continue to use his weapon, the icon at the bottom left hand of the screen will be the fist icon.
 * Despite seemingly lethal actions, targets will merely appear to be in a subdued state and will not be counted as a death, thus enabling Ezio to "kill" civilians. However, during missions these lethal actions will count as a kill to the person that is struck by one. In addition, picking up a body in this subdued state and dropping them a short distance, will cause them to die.
 * In Assassin's Creed: Brotherhood, the Metal Cestus is automatically equipped when Ezio buys the Climb Leap Glove (6100 florins) from Leonardo da Vinci.

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