User blog comment:D. Cello/Assassinews 10/11 -- Desmond's Ancestry Revealed/@comment-78.149.154.111-20111013204129/@comment-1891670-20111013205030

Unregistered contributor: stop spreading lies. He will have a daughter and a son with Sofia Sorto (Flavia and Marcello Auditore, as Jackadorspatacus already mentioned. This has been sourced and confirmed by Ubisoft)