User blog comment:Subject 16*/Assassin's Creed: Revelations - News/@comment-3349505-20110513212710/@comment-3349505-20110514182133

Well, there was writing all over the walls in different languages, so that means that he was jumping through many different ancestors. Subject 16 probably thought he was like 7 or 8 different ancestors at the same time and that caused his mind to go nuts so he killed himself.