User blog comment:TranquilTempest/Perotto Calderon's Son...../@comment-3141192-20101120142646/@comment-5574039-20101122075129

That makes sense. Perhaps Perotto's son went on to have children and his descendants are just as closely linked to the Superhumans as Desmond is. Desmond is one of the few 'true' Assassins left, so there may be a few others in that boat, too.