Mamluks

The Mamluks were a originally soldiers of slave origins, but by 1250 were the rulers of the Mamluk Sultanate, stretching from regions of Egypt to Saudi Arabia and the Levant.

During the early 16th century, the Mamluks had heavy conflicts with the Assassins, namely the Egyptian Assassins and Levantine Assassins. The Mamluks actively tried to undermine the Assassins' recruiting efforts in Jerusalem, capturing their leader Mujir in the process. He was freed by the Assassins without the use of violence, and the Assassins continued recruiting new apprentices.

Source

 * Assassin's Creed: Revelations - Mediterranean Defense