User blog comment:D. Cello/Assassinews 03/05 -- ACWiki's Fan Section and AC3 first trailer/@comment-182.239.197.102-20120307083538/@comment-1153722-20120308174410

Just because Ubisoft didn't pick the setting to everyone's liking doesn't mean you can just shove it to the stereotype "every game is set in America". Let's see what they do with the game first before judging, eh? I personally am very interested in the storyline, and how they are going to blend the Assassins and Templars into the revolution.

This isn't the last game either, no doubt we will explore more settings in the future. We've had Asia (the Middle East, specifically), Europe, and now North America. What would be left are Africa (perhaps Eden?) and east Asia, and maybe South America and Oceania.