User blog comment:Subject 16*/Assassin's Creed: Revelations - News/@comment-121.245.16.86-20110511130448/@comment-3967387-20110511230935

I think it's a possibility that that might happen somhow. It does say in Game Informer that there is a key moment Desmond's history in which the three of them are aligned, and that's what will repair his mind and wake him up.