User blog comment:Master Sima Yi/Assassinews 05-08-'14 – Assassin's Creed: Rogue announced/@comment-24760042-20140809144139/@comment-27202257-20140809183818

Can't speak for a fictional/historical character, but I'm not sure how up to procreating Anne would be during the time she was rolling with Edward, after what happened to her first child.