No Laughing Matter

No Laughing Matter was a virtual representation of one of Ezio Auditore da Firenze's genetic memories, relived by Desmond Miles in 2012 through the Animus.

Description
Ezio Auditore received a contract from Lorenzo de' Medici to assassinate several of Francesco Salviati's fellow conspirators who were hiding in Venice during the Carnevale, posing as minstrels.

Outcome
Ezio followed the thief to the destination and assassinated the target, completing the contract.

Reference

 * Assassin's Creed II