Domenico (disambiguation)

Domenico may refer to:
 * Domenico: a 15th century Italian Assassin.
 * Domenico Auditore: the founder of the Auditore family.
 * Domenico Garofoli: the Venetian Governor of Cyprus.
 * Domenico Ghirlandaio: a Florentine painter.
 * Domenico Maria Novara da Ferrara: an Italian astronomer and mathematician.
 * Domenico da Padova: a high ranking Borgia guard.