Assassination target

Assassination targets were individuals that the Assassin Order – and in select instances, the Templar Order – deemed necessary of elimination.

Middle Ages
Around the time of the Third Crusade, the Assassin Altaïr Ibn-La'Ahad assassinated certain figures during his quest to find The Chalice:
 * Tamir
 * Alaat
 * Roland Napule
 * The Master's Student
 * Master of the Tower
 * Harash
 * Lord Basilisk

Altaïr later assassinated nine tyrannical public figures in an effort to restore his lost rank and regain honor within the Assassin Order:
 * Tamir
 * Garnier de Naplouse
 * Talal
 * Abu'l Nuqoud
 * William of Montferrat
 * Majd Addin
 * Sibrand
 * Jubair al Hakim
 * Maria Thorpe (spared)
 * Robert de Sable

Altaïr also had other targets:
 * Haras
 * Rashid ad-Din Sinan
 * Frederick the Red
 * Moloch
 * Dark Oracle
 * Shalim
 * Shahar
 * Pirate Captain
 * Armand Bouchart
 * Swami
 * Abbas Sofian

These targets, apart from Haras, Rashid ad-Din Sinan, Swami, and Abbas Sofian, were necessary to aid the Cypriot Resistance in the liberation of Cyprus.

Renaissance
During the Renaissance, the Assassin Ezio Auditore da Firenze assassinated several noblemen in order to avenge the deaths of his family members, free the Spanish Assassins, complete his father's life's work, save the Italian cities of Florence, Venice and Rome from corruption, and to fulfill his destiny as an Assassin.
 * Uberto Alberti
 * Vieri de' Pazzi
 * Francesco de' Pazzi
 * Antonio Maffei
 * Francesco Salviati
 * Bernardo Baroncelli
 * Stefano da Bagnone
 * Jacopo de' Pazzi
 * Emilio Barbarigo
 * Carlo Grimaldi
 * Marco Barbarigo
 * Silvio Barbarigo
 * Dante Moro
 * Ludovico Orsi
 * Checco Orsi
 * Gaspar Martínez
 * Pedro Llorente
 * Juan de Marillo
 * Tomás de Torquemada (escaped)
 * Girolamo Savonarola
 * The Painter
 * The Doctor
 * The Preacher
 * The Farmer
 * The Condottiero
 * The Merchant
 * The Nobleman
 * The Priest
 * The Captain Guard
 * Rodrigo Borgia (spared)
 * Master of the Sacred Palace
 * Luigi Torcelli
 * Juan Borgia the Elder
 * Octavian de Valois
 * Micheletto Corella (spared)
 * Ercole Massimo
 * Cesare Borgia

Ezio also completed several Templar agent assassination assignments while liberating the city of Rome.
 * Il Carnefice
 * Malfatto, via an apprentice
 * Silvestro Sabbatini, via an apprentice
 * Lanz
 * Gaspar de la Croix
 * Lia de Russo
 * Donato Mancini
 * Auguste Oberlin
 * Brother Ristoro

Ezio assassinated several Templars and some noblemen in the cities of Masyaf, Constantinople, and Derinkuyu.
 * Leandros
 * Halim
 * Tarik Barleti
 * Shahkulu
 * Manuel Palaiologos

Ezio, with the aid of his Apprentices, also assassinated Templar agents in the city of Constantinople.
 * Vali cel Tradat by an Apprentice
 * Cyril of Rhodes
 * Georgios Kostas by an Apprentice
 * Odai Dunqas by an Apprentice
 * Damat Ali Pasha by an Apprentice
 * Mirela Djuric
 * Lysistrata

Colonial America
Haytham Kenway was responsible for the assassination of two English military operatives, as well as three men that opposed the Templars during the French and Indian War.
 * Miko
 * Louis Mills
 * Cutter
 * Silas Thatcher
 * Edward Braddock

Aveline de Grandpré had seven targets between the French and Indian War and the American Revolutionary War.
 * Jean-Jacques Blaise d'Abbadie
 * Baptiste
 * Antonio de Ulloa (spared)
 * Rafael Joaquín de Ferrer
 * Vásquez
 * George Davidson
 * Madeleine de l'Isle
 * Chapperon

Before, during, and after the events of the American Revolution, the Assassin Ratonhnhaké:ton assassinated several men in order to protect his tribe and further the pursuit of freedom for the citizens of the thirteen British colonies of America.
 * William Johnson
 * John Pitcairn
 * Thomas Hickey
 * Man-Of-War Captain
 * Nicholas Biddle
 * Benjamin Church
 * Kanen'tó:kon
 * Haytham Kenway
 * Charles Lee

Following a meeting with George Washington, Ratonhnhaké:ton found himself in an alternate reality created by an Apple of Eden. During the events contained within, he assassinated the following individuals:
 * Benedict Arnold
 * Benjamin Franklin (spared)
 * Israel Putnam
 * John Fitzwilliams
 * George Washington

Golden Age of Piracy
Edward Kenway, father of Haytham and grandfather of Ratonhnhaké:ton assassinated several men during the Golden Age of Piracy in his quests for riches and glory.
 * Duncan Walpole
 * Julien du Casse
 * Laurens Prins
 * Peter Chamberlaine
 * Charles Vane (spared)
 * Josiah Burgess
 * John Cockram
 * Benjamin Hornigold
 * Woodes Rogers (survived)
 * Bartholomew Roberts
 * El Tiburón
 * Laureano de Torres y Ayala

Furthermore, after selling the names of Master Assassins to the Templar Grand Master Laureano Torres y Ayala, Edward aided these assassins by eliminating several templars:
 * Hilary Flint
 * Vance Travers
 * Jing Lang
 * Lucia Márquez
 * Kenneth Abraham

Adéwalé, a member of the Assassin Order, also assassinated certain individuals.
 * Pierre, Marquis de Fayet

Modern times
The Assassin Desmond Miles infiltrated the Templar company headquarters of Abstergo Industries in Rome, where he assassinated two members of their order. Before this, Desmond also killed an Assassin that had defected to the Templars, following the acquisition of the Apple of Eden in the Colosseum Vault.
 * Lucy Stillman
 * Daniel Cross
 * Warren Vidic